The guys are presently being held in Texas after a civil rights organisation filed a lawsuit to prevent their departure, claiming they were unable to challenge their charges in court.
Using the 1798 Alien Enemies Act, which gives the president the authority to arrest and deport natives or residents of "enemy" countries without following the customary procedures, Donald Trump has sent suspected Venezuelan gang members to an infamous jail in El Salvador. Only three times before, during times of war, has the legislation been invoked.
Challenges to applying the legislation to mass deportations were referred to as "meritless litigation" by the White House.
"We are confident in the lawfulness of the administration's actions and in ultimately prevailing against an onslaught of meritless litigation brought by radical activists who care more about the rights of terrorist aliens than those of the American people," White House Press Secretary Karoline Leavitt wrote in a post on X.
When thousands of persons of Japanese origin were transported to internment camps and imprisoned without trial during World War Two, the Alien Enemies Act was last used.
Trump's strict immigration policies have faced many judicial challenges since he took office in January.
"Perpetrating, attempting, and threatening an invasion or predatory incursion" on US soil was the charge Trump levelled against the Venezuelan gang Tren de Aragua.
According to a senior administration source who spoke to CBS News, the BBC's US news partner, 137 of the 261 Venezuelans deported to El Salvador as of April 8 were taken out under the Alien Enemies Act.
On March 15, a lower court temporarily halted these deportations.
On April 8, the Supreme Court first decided that Trump may deport suspected gang members under the Alien Enemies Act, but that those who are deported must be given the opportunity to contest their deportation.
Despite one inmate spoke only Spanish, the complaint that led to Saturday's ruling claimed that the Venezuelans held in north Texas had received warnings about their impending deportation in English.
The men had not been informed that they had the right to dispute the ruling in court, according to the American Civil Liberties Union's (ACLU) lawsuit.
"Without this Court's intervention, dozens or hundreds of proposed class members may be removed to a possible life sentence in El Salvador with no real opportunity to contest their designation or removal," the complaint said.
Justices Samuel Alito and Clarence Thomas of the Supreme Court dissented on Saturday.
Trump promised to "eliminate the presence of all foreign gangs and criminal networks bringing devastating crime to US soil" during his second inaugural speech in January.
Kilmar Ábrego García, a native of El Salvador, was wrongfully deported by the government in the most well-known instance. However, his family and attorney deny that he is a member of the MS-13 gang. There has never been a conviction for any offence against Mr. Ábrego García.
The Trump administration has said that Mr. Ábrego García would "never" reside in the United States again, despite the Supreme Court's unanimous decision that the government should help bring him back.
During his visit to El Salvador, Senator Chris Van Hollen, a Democrat from Maryland, informed Mr. Ábrego García that he had been transferred from the massive prison known as Cecot (Terrorism Confinement Centre) to a new facility.
